Viral evasion of the integrated stress response through antagonism of eIF2-P binding to eIF2B
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DOI: 10.1038/s41467-021-26164-4
Abstract: Viral infection triggers activation of the integrated stress response (ISR). In response to viral double-stranded RNA (dsRNA), RNA-activated protein kinase (PKR) phosphorylates the translation initiation factor eIF2, converting it from a translation initiator into a… read more here.
Keywords: response; stress response; eif2 binding; viral evasion ... See more keywords