High protein expression of MDS1 and EVI1 complex locus (MECOM) is prognostically adverse and independent of chromosome 3 rearrangements in acute myelogenous leukemia
Sign Up to like & getrecommendations! Published in 2025 at "Blood"
DOI: 10.1182/blood-2025-5258
Abstract: INTRODUCTION: The MDS1 and EVI1 Complex Locus (MECOM), located at chromosome 3q26.2 is rearranged (MECOM-R) in ~1.5% of Acute Myelogenous Leukemia (AML) cases, and confers an adverse prognosis. MECOM-R causes overexpression of Ecotropic viral integration… read more here.
Keywords: evi high; ch3; protein; evi1 ... See more keywords