Creatine kinase pathway inhibition alters GSK3 and WNT signaling in EVI1-positive AML
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DOI: 10.1038/s41375-018-0291-x
Abstract: Over the past decade, several inhibitors of key metabolic dependencies have been shown to be active in AML (Acute Myeloid Leukemia), suggesting that targeting cellular metabolism is a promising therapeutic strategy for this disease. Specific… read more here.
Keywords: creatine; evi1 positive; inhibition; positive aml ... See more keywords