Evidence for altered dendritic spine compartmentalization in Alzheimer’s disease and functional effects in a mouse model
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DOI: 10.1007/s00401-018-1847-6
Abstract: Alzheimer’s disease (AD) is associated with a progressive loss of synapses and neurons. Studies in animal models indicate that morphological alterations of dendritic spines precede synapse loss, increasing the proportion of large and short (“stubby”)… read more here.
Keywords: compartmentalization; alzheimer disease; altered dendritic; evidence altered ... See more keywords
Evidence of Altered Peripheral Nerve Function in a Rodent Model of Diet-Induced Prediabetes
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DOI: 10.3390/biomedicines8090313
Abstract: Peripheral neuropathy (PN) is a debilitating complication of diabetes that affects >50% of patients. Recent evidence suggests that obesity and metabolic disease, which often precede diabetes diagnosis, may influence PN onset and severity. We examined… read more here.
Keywords: evidence altered; nerve; model; nerve function ... See more keywords