In silico evidence of direct interaction between statins and β‐amyloid
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27761
Abstract: Aggregation of amyloid‐β (Aβ) peptides represents a crucial step in the pathogenesis of Alzheimer disease (AD). Compelling evidence from preclinical studies has established that statins may reduce amyloidogenesis and Aβ‐mediated neurodegeneration, supporting a potential role… read more here.
Keywords: evidence direct; interaction statins; silico evidence; direct interaction ... See more keywords
Evidence for a direct link between PAD4-mediated citrullination and the oxidative burst in human neutrophils
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-33385-z
Abstract: Neutrophils are critical for the defense against pathogens, in part through the extrusion of extracellular DNA traps, phagocytosis, and the production of reactive oxygen species. Neutrophils may also play an important role in the pathogenesis… read more here.
Keywords: citrullination; pad4; oxidative burst; activation ... See more keywords