Pre-clinical evidence for the therapeutic effect of Pitaya (Hylocereus lemairei) on diabetic intestinal microenvironment
Sign Up to like & getrecommendations! Published in 2022 at "Natural Product Research"
DOI: 10.1080/14786419.2022.2110091
Abstract: Abstract Intestinal glucose absorption plays a central role in the regulation of glucose plasmatic; however, current clinical management does not target the gut for treating diabetes. This study evaluated the effects of peel and pulp… read more here.
Keywords: clinical evidence; evidence therapeutic; hylocereus; hylocereus lemairei ... See more keywords
Preclinical evidence for the therapeutic value of TBX5 normalization in arrhythmia control
Sign Up to like & getrecommendations! Published in 2020 at "Cardiovascular Research"
DOI: 10.1093/cvr/cvaa239
Abstract: Abstract Aims Arrhythmias and sudden cardiac death (SCD) occur commonly in patients with heart failure. We found T-box 5 (TBX5) dysregulated in ventricular myocardium from heart failure patients and thus we hypothesized that TBX5 reduction… read more here.
Keywords: arrhythmia; tbx5; control; preclinical evidence ... See more keywords
In vivo Evidence for Therapeutic Properties of Cannabidiol (CBD) for Alzheimer's Disease
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DOI: 10.3389/fphar.2017.00020
Abstract: Alzheimer's disease (AD) is a debilitating neurodegenerative disease that is affecting an increasing number of people. It is characterized by the accumulation of amyloid-β and tau hyperphosphorylation as well as neuroinflammation and oxidative stress. Current… read more here.
Keywords: vivo evidence; alzheimer disease; disease; cannabidiol cbd ... See more keywords
Preclinical and Clinical Evidence of Therapeutic Agents for Paclitaxel-Induced Peripheral Neuropathy
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DOI: 10.3390/ijms22168733
Abstract: Paclitaxel is an essential drug in the chemotherapy of ovarian, non-small cell lung, breast, gastric, endometrial, and pancreatic cancers. However, it frequently causes peripheral neuropathy as a dose-limiting factor. Animal models of paclitaxel-induced peripheral neuropathy… read more here.
Keywords: paclitaxel induced; peripheral neuropathy; clinical evidence; induced peripheral ... See more keywords