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Published in 2022 at "Natural Product Research"
DOI: 10.1080/14786419.2022.2110091
Abstract: Abstract Intestinal glucose absorption plays a central role in the regulation of glucose plasmatic; however, current clinical management does not target the gut for treating diabetes. This study evaluated the effects of peel and pulp…
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Keywords:
clinical evidence;
evidence therapeutic;
hylocereus;
hylocereus lemairei ... See more keywords
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Published in 2020 at "Cardiovascular Research"
DOI: 10.1093/cvr/cvaa239
Abstract: Abstract Aims Arrhythmias and sudden cardiac death (SCD) occur commonly in patients with heart failure. We found T-box 5 (TBX5) dysregulated in ventricular myocardium from heart failure patients and thus we hypothesized that TBX5 reduction…
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Keywords:
arrhythmia;
tbx5;
control;
preclinical evidence ... See more keywords
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Published in 2017 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2017.00020
Abstract: Alzheimer's disease (AD) is a debilitating neurodegenerative disease that is affecting an increasing number of people. It is characterized by the accumulation of amyloid-β and tau hyperphosphorylation as well as neuroinflammation and oxidative stress. Current…
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Keywords:
vivo evidence;
alzheimer disease;
disease;
cannabidiol cbd ... See more keywords
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Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22168733
Abstract: Paclitaxel is an essential drug in the chemotherapy of ovarian, non-small cell lung, breast, gastric, endometrial, and pancreatic cancers. However, it frequently causes peripheral neuropathy as a dose-limiting factor. Animal models of paclitaxel-induced peripheral neuropathy…
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Keywords:
paclitaxel induced;
peripheral neuropathy;
clinical evidence;
induced peripheral ... See more keywords
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Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms25042124
Abstract: The human retina is a complex anatomical structure that has no regenerative capacity. The pathogenesis of most retinopathies can be attributed to inflammation, with the activation of the inflammasome protein platform, and to the impact…
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Keywords:
therapeutic strategies;
classical innovative;
retinal dysfunctions;
innovative evidence ... See more keywords