Potential Role of the Fragile Histidine Triad in Cancer Evo-Dev
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DOI: 10.3390/cancers15041144
Abstract: Simple Summary Tumor development follows an evolutionary pattern of “mutation-selection-adaptation”, characterized by exogenous oncogenic induction and endogenous replicative stress. The fragile histidine triad (FHIT) is a tumor suppressor. Aberrant transcription or reduction in the transcription… read more here.
Keywords: evo dev; role; histidine triad; cancer evo ... See more keywords