A screening campaign in sea urchin egg homogenate as a platform for discovering modulators of NAADP-dependent Ca2+ signaling in human cells
Sign Up to like & getrecommendations! Published in 2018 at "Cell Calcium"
DOI: 10.1016/j.ceca.2018.08.002
Abstract: Abstract The Ca2+ mobilizing second messenger nicotinic acid adenine dinucleotide phosphate (NAADP) regulates intracellular trafficking events, including translocation of certain enveloped viruses through the endolysosomal system. Targeting NAADP-evoked Ca2+ signaling may therefore be an effective… read more here.
Keywords: naadp evoked; system; ca2 signaling; sea urchin ... See more keywords
β3‐adrenoceptor agonists inhibit carbachol‐evoked Ca2+ oscillations in murine detrusor myocytes
Sign Up to like & getrecommendations! Published in 2018 at "BJU International"
DOI: 10.1111/bju.14090
Abstract: To test if carbachol (CCh)‐evoked Ca2+ oscillations in freshly isolated murine detrusor myocytes are affected by β3‐adrenoceptor (β‐AR) modulators. read more here.
Keywords: evoked ca2; carbachol; murine detrusor; ca2 oscillations ... See more keywords
Endogenous signalling pathways and caged IP3 evoke Ca2+ puffs at the same abundant immobile intracellular sites
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cell Science"
DOI: 10.1242/jcs.208520
Abstract: ABSTRACT The building blocks of intracellular Ca2+ signals evoked by inositol 1,4,5-trisphosphate receptors (IP3Rs) are Ca2+ puffs, transient focal increases in Ca2+ concentration that reflect the opening of small clusters of IP3Rs. We use total… read more here.
Keywords: ca2 puffs; signalling pathways; caged ip3; evoked ca2 ... See more keywords