Antidepressants Are Poor Inhibitors of Heat-Evoked Ion Currents Mediated by TRPM2
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DOI: 10.1159/000524934
Abstract: Introduction: The heat and redox-sensitive ion channel TRPM2 was reported to be a causative mechanism for depression in a mouse model and to be upregulated in the hippocampus in patients suffering from depressive disorders. TRPM2… read more here.
Keywords: inhibition; evoked currents; trpm2; heat ... See more keywords
Nitric oxide modulates ATP-evoked currents in mouse Leydig cells
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DOI: 10.1590/1414-431x20186693
Abstract: Testosterone synthesis within Leydig cells is a calcium-dependent process. Intracellular calcium levels are regulated by different processes including ATP-activated P2X purinergic receptors, T-type Ca2+ channels modulated by the luteinizing hormone, and intracellular calcium storages recruited… read more here.
Keywords: atp evoked; oxide modulates; evoked currents; calcium ... See more keywords