Diverse aging rates in ectothermic tetrapods provide insights for the evolution of aging and longevity
Sign Up to like & getrecommendations! Published in 2022 at "Science"
DOI: 10.1126/science.abm0151
Abstract: Comparative studies of mortality in the wild are necessary to understand the evolution of aging; yet, ectothermic tetrapods are underrepresented in this comparative landscape, despite their suitability for testing evolutionary hypotheses. We present a study… read more here.
Keywords: diverse aging; reptiles amphibians; evolution aging; ectothermic tetrapods ... See more keywords
Can Aging Develop as an Adaptation to Optimize Natural Selection? (Application of Computer Modeling for Searching Conditions When the “Fable of Hares” Can Explain the Evolution of Aging)
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DOI: 10.1134/s0006297918120088
Abstract: There are two points of view on the evolution of aging. The classical theory of aging suggests that natural selection does not efficiently eliminate mutations or alleles that are harmful to organisms at later age.… read more here.
Keywords: adaptation; fable hares; evolution aging; natural selection ... See more keywords
ALS/FTD: Evolution, Aging, and Cellular Metabolic Exhaustion
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.890203
Abstract: Amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD) are neurodegenerations with evolutionary underpinnings, expansive clinical presentations, and multiple genetic risk factors involving a complex network of pathways. This perspective considers the complex cellular pathology of aging… read more here.
Keywords: cellular metabolic; evolution aging; als ftd; aging cellular ... See more keywords