Possible Role of the Polyglutamine Elongation in Evolution of Amyloid-Related Evolvability
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DOI: 10.3233/jhd-180309
Abstract: The polyglutamine (polyQ) diseases, such as Huntington’s disease and the spinocerebellar ataxias, are characterized by the accumulation of elongated polyQ sequences (epolyQ) and mostly occur during midlife. Considering that polyQ disorders have not been selected… read more here.
Keywords: amyloid related; physiological functions; evolvability; disease ... See more keywords