[Directed evolution in drug and antibody development : From the Nobel Prize to broad clinical application].
Sign Up to like & getrecommendations! Published in 2019 at "Der Internist"
DOI: 10.1007/s00108-019-00675-1
Abstract: Combinatorial procedures have become established in recent years as alternatives to rational design in drug research, particularly when no structural information is available. This article presents the principle that was originally developed by three scientists… read more here.
Keywords: drug; application; directed evolution; evolution drug ... See more keywords
Evolution of drug-eluting coronary stents: a back-and-forth journey from the bench-to-bedside.
Sign Up to like & getrecommendations! Published in 2022 at "Cardiovascular research"
DOI: 10.1093/cvr/cvac105
Abstract: Coronary stents have revolutionized the treatment of coronary artery disease. Compared with balloon angioplasty, bare-metal stents effectively prevented abrupt vessel closure but were limited by in-stent restenosis due to smooth muscle cell proliferation and neointimal… read more here.
Keywords: stent design; drug eluting; evolution drug; coronary stents ... See more keywords