Evolution-Guided Biosynthesis of Terpenoid Inhibitors.
Sign Up to like & getrecommendations! Published in 2022 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.2c00188
Abstract: Terpenoids, the largest and most structurally diverse group of natural products, include a striking variety of biologically active compounds, from flavors to medicines. Despite their well-documented biochemical versatility, the evolutionary processes that generate new functional… read more here.
Keywords: guided biosynthesis; terpenoid inhibitors; biosynthesis terpenoid; evolution guided ... See more keywords
Evolution-guided protein design of IscB for persistent epigenome editing in vivo.
Sign Up to like & getrecommendations! Published in 2025 at "Nature biotechnology"
DOI: 10.1038/s41587-025-02655-3
Abstract: Naturally existing enzymes have been adapted for a variety of molecular technologies, with enhancements or modifications to the enzymes introduced to improve the desired function; however, it is difficult to engineer variants with enhanced activity… read more here.
Keywords: protein design; guided protein; evolution guided; design iscb ... See more keywords
Understanding the evolution of the guided tours: the case of Türkiye
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Tourism and Cultural Change"
DOI: 10.1080/14766825.2025.2453227
Abstract: ABSTRACT This research aims to explore the development and evolution of guided tours over recent decades. Focusing on the perspectives of professional tour guides regarding changes in their professional features over the past 30 years,… read more here.
Keywords: case rkiye; guided tours; evolution guided; tours case ... See more keywords