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Evolution of a highly functional circular DNA aptamer in serum

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Published in 2020 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkaa800

Abstract: Abstract Circular DNA aptamers are powerful candidates for therapeutic applications given their dramatically enhanced biostability. Herein we report the first effort to evolve circular DNA aptamers that bind a human protein directly in serum, a… read more here.

Keywords: circular dna; dna; serum; dna aptamers ... See more keywords