Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase.
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DOI: 10.1016/j.molcel.2019.06.046
Abstract: Endonuclease V (EndoV) cleaves the second phosphodiester bond 3' to a deaminated adenosine (inosine). Although highly conserved, EndoV homologs change substrate preference from DNA in bacteria to RNA in eukaryotes. We have characterized EndoV from… read more here.
Keywords: endonuclease; inosine specific; endov homologs; inosine ... See more keywords