An evolution-inspired strategy to design disulfide-rich peptides tolerant to extensive sequence manipulation
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Science"
DOI: 10.1039/d1sc02952e
Abstract: Natural disulfide-rich peptides (DRPs) are valuable scaffolds for the development of new bioactive molecules and therapeutics. However, there are only a limited number of topologically distinct DRP folds in nature, and most of them suffer… read more here.
Keywords: evolution inspired; strategy design; disulfide; disulfide rich ... See more keywords