Directed Evolution of P450 BM3 towards Functionalization of Aromatic O-Heterocycles
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DOI: 10.3390/ijms20133353
Abstract: The O-heterocycles, benzo-1,4-dioxane, phthalan, isochroman, 2,3-dihydrobenzofuran, benzofuran, and dibenzofuran are important building blocks with considerable medical application for the production of pharmaceuticals. Cytochrome P450 monooxygenase (P450) Bacillus megaterium 3 (BM3) wild type (WT) from Bacillus… read more here.
Keywords: evolution p450; p450 bm3; bm3; directed evolution ... See more keywords