Oxytocin‐like receptor expression in evolutionarily conserved nodes of a vocal network associated with male courtship in a teleost fish
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25257
Abstract: Neuropeptides, including oxytocin‐like peptides, are a conserved group of hormones that regulate a wide range of social behaviors, including vocal communication. In the current study, we evaluate whether putative brain sites for the actions of… read more here.
Keywords: poa; evolutionarily conserved; oxytocin like; male courtship ... See more keywords
The Stress-Responding miR-132-3p Shows Evolutionarily Conserved Pathway Interactions
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and Molecular Neurobiology"
DOI: 10.1007/s10571-017-0515-z
Abstract: MicroRNAs (miRNAs) are small non-coding RNA chains that can each interact with the 3′-untranslated region of multiple target transcripts in various organisms, humans included. MiRNAs tune entire biological pathways, spanning stress reactions, by regulating the… read more here.
Keywords: mir 132; evolutionarily conserved; stress related; stress ... See more keywords
Lhx2, an evolutionarily conserved, multifunctional regulator of forebrain development
Sign Up to like & getrecommendations! Published in 2018 at "Brain research"
DOI: 10.1016/j.brainres.2018.02.046
Abstract: A hundred years after Lhx2 ortholog apterous was identified as a critical regulator of wing development in Drosophila, LIM-HD gene family members have proved to be versatile and powerful components of the molecular machinery that… read more here.
Keywords: forebrain; evolutionarily conserved; lhx2 evolutionarily; factor ... See more keywords
NOTCH signaling: Journey of an evolutionarily conserved pathway in driving tumor progression and its modulation as a therapeutic target.
Sign Up to like & getrecommendations! Published in 2021 at "Critical reviews in oncology/hematology"
DOI: 10.1016/j.critrevonc.2021.103403
Abstract: Notch signaling, an evolutionarily conserved signaling cascade, is critical for normal biological processes of cell differentiation, development, and homeostasis. Deregulation of the Notch signaling pathway has been associated with tumor progression. Thus, Notch presents as… read more here.
Keywords: tumor progression; notch signaling; notch; evolutionarily conserved ... See more keywords
The Evolutionarily Conserved Cassette Exon 7b Drives ERG's Oncogenic Properties
Sign Up to like & getrecommendations! Published in 2019 at "Translational Oncology"
DOI: 10.1016/j.tranon.2018.09.001
Abstract: The oncogene ERG encodes an ETS family transcription factor and is implicated in blood, vascular, and bone development and in prostate, blood, and bone cancer. The ERG gene is alternatively spliced; of particular interest is… read more here.
Keywords: evolutionarily conserved; erg oncogenic; exon; cassette exon ... See more keywords
Ubiquitin-Proteasome System Regulation of an Evolutionarily Conserved RNA Polymerase II-Associated Factor 1 Involved in Pancreatic Oncogenesis.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry"
DOI: 10.1021/acs.biochem.7b00865
Abstract: The evolutionarily conserved RNA polymerase II-associated factor 1 (Paf1) from yeast to humans regulates transcription and associated processes, and thus, malfunctions and/or misregulations of Paf1 are associated with cellular pathologies. Indeed, Paf1 (also known as… read more here.
Keywords: evolutionarily conserved; rna polymerase; factor; conserved rna ... See more keywords
The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2112225119
Abstract: Significance The hypocretin (Hcrt, also known as orexin) neuropeptides regulate sleep and wake stability, and disturbances of Hcrt can lead to sleep disorders. MicroRNAs (miRNAs) are short noncoding RNAs that fine-tune protein expression levels, and… read more here.
Keywords: sleep wake; conserved mirna; mirna 137; mir 137 ... See more keywords
From evolutionarily conserved frontal regions for sequence processing to human innovations for syntax
Sign Up to like & getrecommendations! Published in 2018 at "Interaction Studies"
DOI: 10.1075/is.17038.wil
Abstract: Abstract Empirical advances have been made in understanding how human language, in its combinatorial complexity and unbounded expressivity, may have evolved from the communication systems present in our evolutionary ancestors. However, a number of cognitive… read more here.
Keywords: evolutionarily conserved; conserved frontal; frontal regions; syntax ... See more keywords
INP1 involvement in pollen aperture formation is evolutionarily conserved and may require species-specific partners
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Experimental Botany"
DOI: 10.1093/jxb/erx407
Abstract: The role of INP1as a pollen aperture factor seems to be evolutionarily conserved but may need species-specific partners. The central portion of INP1 is particularly important for species-specific functionality. read more here.
Keywords: pollen aperture; evolutionarily conserved; specific partners; species specific ... See more keywords
Evolutionarily conserved role of oxytocin in social fear contagion in zebrafish
Sign Up to like & getrecommendations! Published in 2023 at "Science"
DOI: 10.1126/science.abq5158
Abstract: Emotional contagion is the most ancestral form of empathy. We tested to what extent the proximate mechanisms of emotional contagion are evolutionarily conserved by assessing the role of oxytocin, known to regulate empathic behaviors in… read more here.
Keywords: contagion zebrafish; contagion; role; conserved role ... See more keywords
Evolutionarily conserved transcription factors as regulators of longevity and targets for geroprotection.
Sign Up to like & getrecommendations! Published in 2022 at "Physiological reviews"
DOI: 10.1152/physrev.00017.2021
Abstract: Aging is the single largest risk factor for many debilitating conditions, including heart diseases, stroke, cancer, diabetes, and neurodegenerative disorders. While far from understood in its full complexity, it is scientifically well-established that aging is… read more here.
Keywords: transcription; factors regulators; regulators longevity; conserved transcription ... See more keywords