Predicting Evolutionary Constraints by Identifying Conflicting Demands in Regulatory Networks.
Sign Up to like & getrecommendations! Published in 2020 at "Cell systems"
DOI: 10.1016/j.cels.2020.05.004
Abstract: Gene regulation networks allow organisms to adapt to diverse environmental niches. However, the constraints underlying the evolution of gene regulation remain ill defined. Here, we show that partial order-a concept that ranks network output levels… read more here.
Keywords: network; identifying conflicting; constraints identifying; conflicting demands ... See more keywords
Evolutionary constraints on the complexity of genetic regulatory networks allow predictions of the total number of genetic interactions
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-39866-z
Abstract: Genetic regulatory networks (GRNs) have been widely studied, yet there is a lack of understanding with regards to the final size and properties of these networks, mainly due to no network currently being complete. In… read more here.
Keywords: network; genetic regulatory; number; regulatory networks ... See more keywords