Evolutionary divergent kinetoplast genome structure and RNA editing patterns in the trypanosomatid Vickermania
Sign Up to like & getrecommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2426887122
Abstract: Significance The study of trypanosomatid flagellates has continually broadened our knowledge of eukaryotic biology and highlighted the limits of our assumptions based on model organisms. The impacts of gains and losses of DNA units, such… read more here.
Keywords: structure rna; genome structure; evolutionary divergent; rna ... See more keywords
Evolutionary divergent clusters of transcribed extinct truncated retroposons drive low mRNA expression and developmental regulation in the protozoan Leishmania
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DOI: 10.1186/s12915-024-02051-4
Abstract: The Leishmania genome harbors formerly active short interspersed degenerated retroposons (SIDERs) representing the largest family of repetitive elements among trypanosomatids. Their substantial expansion in Leishmania is a strong predictor of important biological functions. In this… read more here.
Keywords: evolutionary divergent; sider2; leishmania; low mrna ... See more keywords