New insights into the evolutionary dynamic and lineage divergence of gasdermin E in metazoa
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DOI: 10.3389/fcell.2022.952015
Abstract: Gasdermin (GSDM) is a family of pore-forming proteins that induce pyroptosis. To date, the origin and evolution of GSDM in Metazoa remain elusive. Here, we found that GSDM emerged early in Placozoa but is absent… read more here.
Keywords: gasdermin; insights evolutionary; recognition motif; caspase recognition ... See more keywords