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Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2425753122
Abstract: We present a simple physical model that recapitulates several features of biological evolution, while being based only on thermally driven attachment and detachment of elementary building blocks. Through its dynamics, this model samples a large…
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Keywords:
evolutionary features;
adaptation;
features minimal;
model ... See more keywords
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Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20153834
Abstract: Alternative splicing of pre-mRNAs is a crucial mechanism for maintaining protein diversity in eukaryotes without requiring a considerable increase of genes in the number. Due to rapid advances in high-throughput sequencing technologies and computational algorithms,…
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Keywords:
spliced exons;
evolutionary features;
alternatively spliced;
sequence evolutionary ... See more keywords