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   Articles with "evolutionary fitness" as a keyword



Energetics and evolutionary fitness

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recommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2423684122

Abstract: It has long been recognized that energy is the currency of evolution, but contrasting conceptions of the relationship between energy and adaptation have yielded different interpretations. In the equal fitness paradigm (EFP), fitness (defined as… read more here.

Keywords: fitness; energetics evolutionary; energy; evolutionary fitness ... See more keywords

Individualistic attitudes in Iterated Prisoner’s Dilemma undermine evolutionary fitness and may drive cooperative human players to extinction

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recommendations! Published in 2024 at "Royal Society Open Science"

DOI: 10.1098/rsos.230867

Abstract: Inarguably, humans perform the richest plethora of prosocial behaviours in the animal kingdom, and these are important for understanding how humans navigate their social environment. The success and failure of strategies human players devise also… read more here.

Keywords: prisoner dilemma; fitness; human players; individualistic attitudes ... See more keywords

Relating pathogenic loss-of-function mutations in humans to their evolutionary fitness costs

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recommendations! Published in 2022 at "eLife"

DOI: 10.1101/2022.08.11.503594

Abstract: Causal loss-of-function (LOF) variants for Mendelian and severe complex diseases are enriched in “mutation intolerant” genes. We show how such observations can be interpreted in light of a model of mutation-selection balance, and use the… read more here.

Keywords: loss function; fitness effects; evolutionary fitness; fitness ... See more keywords

Abstract 3385: Modeling evolutionary fitness in resistant cancers based on a common adaptability trait

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recommendations! Published in 2024 at "Cancer Research"

DOI: 10.1158/1538-7445.am2024-3385

Abstract: Cancer is composed of a major subpopulation of proliferative cells and a minor subpopulation of highly adaptable cells. Although it is evident that cancer is an evolution like process driven by rare adaptable cancer cells… read more here.

Keywords: cancer; culture; resistant cancers; cell ... See more keywords