Articles with "evolutionary structural" as a keyword



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Smoothing evolutionary structural optimization for structures with displacement or natural frequency constraints

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Published in 2018 at "Engineering Structures"

DOI: 10.1016/j.engstruct.2018.02.032

Abstract: Abstract The Smoothing Evolutionary Structural Optimization (SESO) technique was extended to solve 2D elastic problems with constraint of displacements or natural frequencies. At the end of each finite element analysis, a scalar representing the sensitivity… read more here.

Keywords: smoothing evolutionary; optimization; structural optimization; optimization structures ... See more keywords
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A Bi-directional Evolutionary Structural Optimisation algorithm with an added connectivity constraint

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Published in 2017 at "Finite Elements in Analysis and Design"

DOI: 10.1016/j.finel.2017.03.005

Abstract: Abstract This paper proposes the introduction of a connectivity constraint in the Bi-directional Evolutionary Structural Optimisation (BESO) method, which avoids the possibility of arriving at highly non-optimal local optima. By developing a constraint that looks… read more here.

Keywords: directional evolutionary; connectivity constraint; optimisation; structural optimisation ... See more keywords
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Evolutionary and Structural Insights about Potential SARS-CoV-2 Evasion of Nirmatrelvir

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Published in 2022 at "Journal of Medicinal Chemistry"

DOI: 10.1021/acs.jmedchem.2c00404

Abstract: The U.S. FDA approval of PAXLOVID, a combination therapy of nirmatrelvir and ritonavir has significantly boosted our morale in fighting the COVID-19 pandemic. Nirmatrelvir is an inhibitor of the main protease (MPro) of SARS-CoV-2. Since… read more here.

Keywords: structural insights; nirmatrelvir; evasion nirmatrelvir; sars cov ... See more keywords