Evolvability and constraint in the evolution of three‐dimensional flower morphology
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Botany"
DOI: 10.1002/ajb2.16092
Abstract: Abstract Premise Flower phenotypes evolve to attract pollinators and to ensure efficient pollen transfer to and from the bodies of pollinators or, in self‐compatible bisexual flowers, between anthers and stigmas. If functionally interacting traits are… read more here.
Keywords: evolvability; evolution three; genetic constraints; three dimensional ... See more keywords
Genomic Stress Responses Drive Lymphocyte Evolvability: An Ancient and Ubiquitous Mechanism
Sign Up to like & getrecommendations! Published in 2020 at "BioEssays"
DOI: 10.1002/bies.202000032
Abstract: Somatic diversification of antigen receptor genes depends on the activity of enzymes whose homologs participate in a mutagenic DNA repair in unicellular species. Indeed, by engaging error‐prone polymerases, gap filling molecules and altered mismatch repair… read more here.
Keywords: responses drive; evolvability; stress; stress responses ... See more keywords
Prior evolution in stochastic versus constant temperatures affects RNA virus evolvability at a thermal extreme
Sign Up to like & getrecommendations! Published in 2020 at "Ecology and Evolution"
DOI: 10.1002/ece3.6287
Abstract: Abstract It is unclear how historical adaptation versus maladaptation in a prior environment affects population evolvability in a novel habitat. Prior work showed that vesicular stomatitis virus (VSV) populations evolved at constant 37°C improved in… read more here.
Keywords: evolution; evolvability; versus; environment ... See more keywords
Evolutionary Capacitance Emerges Spontaneously during Adaptation to Environmental Changes.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.09.008
Abstract: All biological populations are to a greater or lesser degree evolvable, but the forces that shape evolvability, especially the evolution of evolvability as an adaptive response to pressure to evolve rapidly, are a source of… read more here.
Keywords: capacitance; evolvability; mutational neighborhood; capacitance emerges ... See more keywords
Greedy reduction of Bacillus subtilis genome yields emergent phenotypes of high resistance to a DNA damaging agent and low evolvability
Sign Up to like & getrecommendations! Published in 2023 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkad145
Abstract: Abstract Genome-scale engineering enables rational removal of dispensable genes in chassis genomes. Deviating from this approach, we applied greedy accumulation of deletions of large dispensable regions in the Bacillus subtilis genome, yielding a library of… read more here.
Keywords: evolvability; subtilis genome; bacillus subtilis; high resistance ... See more keywords
Mutational scans reveal differential evolvability of Drosophila promoters and enhancers
Sign Up to like & getrecommendations! Published in 2023 at "Philosophical Transactions of the Royal Society B: Biological Sciences"
DOI: 10.1098/rstb.2022.0054
Abstract: Rapid enhancer and slow promoter evolution have been demonstrated through comparative genomics. However, it is not clear how this information is encoded genetically and if this can be used to place evolution in a predictive… read more here.
Keywords: evolvability; reveal differential; evolvability drosophila; mutational scans ... See more keywords
The effects of stress and sex on selection, genetic covariance, and the evolutionary response
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Evolutionary Biology"
DOI: 10.1111/jeb.13149
Abstract: The capacity of a population to adapt to selection (evolvability) depends on whether the structure of genetic variation permits the evolution of fitter trait combinations. Selection, genetic variance and genetic covariance can change under environmental… read more here.
Keywords: effects stress; evolvability; genetic covariance; selection ... See more keywords
A Retro-Aldol Reaction Prompted the Evolvability of a Phosphotransferase System for the Utilization of a Rare Sugar
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.03660-22
Abstract: Microorganisms generate energy through glycolysis, which might have preceded a rapid burst of evolution, including the evolution of cellular respiration in the primordial biosphere. However, little is known about the evolvability of cellular sugar preferences.… read more here.
Keywords: evolvability; retro aldol; aldol reaction; rare sugar ... See more keywords
Evolution of evolvability and phenotypic plasticity in virtual cells
Sign Up to like & getrecommendations! Published in 2017 at "BMC Evolutionary Biology"
DOI: 10.1186/s12862-017-0918-y
Abstract: BackgroundChanging environmental conditions pose a challenge for the survival of species. To meet this challenge organisms adapt their phenotype by physiological regulation (phenotypic plasticity) or by evolving. Regulatory mechanisms that ensure a constant internal environment… read more here.
Keywords: evolution; virtual cells; evolvability; change ... See more keywords
Historical contingency in the evolution of antibiotic resistance after decades of relaxed selection
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Biology"
DOI: 10.1371/journal.pbio.3000397
Abstract: Populations often encounter changed environments that remove selection for the maintenance of particular phenotypic traits. The resulting genetic decay of those traits under relaxed selection reduces an organism’s fitness in its prior environment. However, whether… read more here.
Keywords: relaxed selection; evolution; evolvability; resistance ... See more keywords
Viral protein instability enhances host-range evolvability
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1010030
Abstract: Viruses are highly evolvable, but what traits endow this property? The high mutation rates of viruses certainly play a role, but factors that act above the genetic code, like protein thermostability, are also expected to… read more here.
Keywords: evolvability; host range; protein; host ... See more keywords