Effect of stroke etiology on endovascular thrombectomy with or without intravenous alteplase: a subgroup analysis of DIRECT-MT
Sign Up to like & getrecommendations! Published in 2022 at "Journal of NeuroInterventional Surgery"
DOI: 10.1136/neurintsurg-2021-018275
Abstract: Background Stroke etiology might influence the clinical outcomes in patients with large vessel occlusion receiving endovascular treatment (EVT) with or without thrombolysis. Objective To examine whether stroke etiology resulted in different efficacy and safety in… read more here.
Keywords: mrs score; stroke etiology; intravenous alteplase; etiology ... See more keywords
Perceived acceptable uncertainty regarding comparability of endovascular treatment alone versus intravenous thrombolysis plus endovascular treatment.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of neurointerventional surgery"
DOI: 10.1136/neurintsurg-2022-018665
Abstract: BACKGROUND Most trials comparing endovascular treatment (EVT) alone versus intravenous thrombolysis with alteplase (IVT) + EVT in directly admitted patients with a stroke are non-inferiority trials. However, the margin based on the level of uncertainty… read more here.
Keywords: versus intravenous; alone versus; endovascular treatment; evt alone ... See more keywords
Endovascular thrombectomy with or without intravenous alteplase for acute ischemic stroke due to large vessel occlusion: a systematic review and meta-analysis of randomized trials
Sign Up to like & getrecommendations! Published in 2022 at "Stroke and Vascular Neurology"
DOI: 10.1136/svn-2022-001547
Abstract: Background Among patients who had an ischaemic stroke presenting directly to a stroke centre where endovascular thrombectomy (EVT) is immediately available, there is uncertainty regarding the role of intravenous thrombolysis agents before or concurrently with… read more here.
Keywords: alteplase; certainty evidence; meta; stroke ... See more keywords
Cost-effectiveness of thrombectomy alone versus alteplase before thrombectomy in acute ischemic stroke: results from the DIRECT-MT.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of neurosurgery"
DOI: 10.3171/2022.12.jns221791
Abstract: OBJECTIVE The use of thrombectomy alone (endovascular thrombectomy [EVT]) was found to be noninferior to combination therapy (EVT plus intravenous thrombolysis [IVT] with alteplase before thrombectomy [EVT+IVT]) in the DIRECT-MT (Direct Intra-Arterial Thrombectomy in Order… read more here.
Keywords: evt alone; thrombectomy; evt ivt; cost effectiveness ... See more keywords
In acute ischemic stroke, EVT alone vs. IV alteplase plus EVT did not differ for functional outcome at 90 d
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Internal Medicine"
DOI: 10.7326/j22-0016
Abstract: SOURCE CITATION LeCouffe NE, Kappelhof M, Treurniet KM, et al. A randomized trial of intravenous alteplase before endovascular treatment for stroke. N Engl J Med. 2021;385:1833-44. 34758251. read more here.
Keywords: alone alteplase; alteplase; stroke evt; acute ischemic ... See more keywords