Wfs1- deficient rats develop primary symptoms of Wolfram syndrome: insulin-dependent diabetes, optic nerve atrophy and medullary degeneration
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DOI: 10.1038/s41598-017-09392-x
Abstract: Wolfram syndrome (WS) is a rare autosomal-recessive disorder that is caused by mutations in the WFS1 gene and is characterized by juvenile-onset diabetes, optic atrophy, hearing loss and a number of other complications. Here, we… read more here.
Keywords: ex5 ko232; ko232 rats; atrophy; wfs1 ex5 ... See more keywords