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An Exceedingly Mild, Green Synthesis of Substituted N‐3‐diaryl‐1,8‐naphthyridin‐2‐amine Derivatives and Their Antimicrobial Activity

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Published in 2018 at "Journal of Heterocyclic Chemistry"

DOI: 10.1002/jhet.3125

Abstract: An exceedingly and highly efficient procedure has been described for the synthesis of substituted N-3-diaryl-1,8-naphthyridin-2-amines by the reaction of 2-chloro-3-aryl-1,8-naphthyridines with various anilines in the presence of N-methyl-2-pyrrolidone and K2CO3 under thermal green solvent-free conditions.… read more here.

Keywords: synthesis substituted; exceedingly mild; substituted diaryl; activity ... See more keywords