New Deferric Amine Compounds Efficiently Chelate Excess Iron to Treat Iron Overload Disorders and to Prevent Ferroptosis
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DOI: 10.1002/advs.202202679
Abstract: Excess iron accumulation occurs in organs of patients with certain genetic disorders or after repeated transfusions. No physiological mechanism is available to excrete excess iron and iron overload to promote lipid peroxidation to induce ferroptosis,… read more here.
Keywords: iron overload; deferric amine; iron; new deferric ... See more keywords
12 Effects of excess iron and dietary fat on lipid metabolism
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DOI: 10.1093/jas/skz258.031
Abstract: Diets rich in fat and energy are associated with metabolic syndrome. Imbalanced systemic iron status has long been epidemiologically associated with obesity-related diseases. The aim of this study is to investigate the interaction between dietary… read more here.
Keywords: high iron; dietary fat; excess iron; iron ... See more keywords
Effects of Excess Iron on the Retina: Insights From Clinical Cases and Animal Models of Iron Disorders
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DOI: 10.3389/fnins.2021.794809
Abstract: Iron plays an important role in a wide range of metabolic pathways that are important for neuronal health. Excessive levels of iron, however, can promote toxicity and cell death. An example of an iron overload… read more here.
Keywords: iron overload; effects excess; iron; retina ... See more keywords
Serving Two Masters: Effect of Escherichia coli Dual Resistance on Antibiotic Susceptibility
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DOI: 10.3390/antibiotics12030603
Abstract: The prevalence of multidrug-resistant bacteria and their increased pathogenicity has led to a growing interest in metallic antimicrobial materials and bacteriophages as potential alternatives to conventional antibiotics. This study examines how resistance to excess iron… read more here.
Keywords: iron; iron iii; iii; resistance ... See more keywords