Articles with "excess synuclein" as a keyword



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Hsc70 Ameliorates the Vesicle Recycling Defects Caused by Excess α-Synuclein at Synapses

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Published in 2020 at "eNeuro"

DOI: 10.1523/eneuro.0448-19.2020

Abstract: α-Synuclein overexpression and aggregation are linked to Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and several other neurodegenerative disorders. In addition to effects in the cell body, α-synuclein accumulation occurs at presynapses where the… read more here.

Keywords: excess synuclein; synaptic vesicle; vesicle recycling; recycling defects ... See more keywords