X-linked myopathy with excessive autophagy due to a mutation in VMA21 gene: the first case in China
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DOI: 10.1007/s10072-021-05788-w
Abstract: Dear Editor, X-linked myopathy with excessive autophagy (XMEA) was firstly reported by Kalimo et al. in 1988 [1]. Five male patients from a Finnish family experienced proximal weakness in both lower extremities from 5–6 years… read more here.
Keywords: excessive autophagy; linked myopathy; gene; vma21 ... See more keywords
Activation of G-protein-coupled receptor 30 protects neurons against excitotoxicity through inhibiting excessive autophagy induced by glutamate.
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DOI: 10.1021/acschemneuro.9b00287
Abstract: Autophagy is a protecting intracellular pathway to transmit unnecessary or dysfunctional components to the lysosome for degeneration. Autophagic imbalance is connected with neurodegeneration. Neurodegenerative diseases including Parkinson's disease, Alzheimer's disease, and Huntington's disease are closely… read more here.
Keywords: neurons excitotoxicity; protects neurons; autophagy; excessive autophagy ... See more keywords
Propofol Upregulates MicroRNA-30b to Inhibit Excessive Autophagy and Apoptosis and Attenuates Ischemia/Reperfusion Injury In Vitro and in Patients
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DOI: 10.1155/2022/2109891
Abstract: Evidence reveals that propofol protects cells via suppressing excessive autophagy induced by hypoxia/reoxygenation (H/R). Previously, we found in a genome-wide microRNA profile analysis that several autophagy-related microRNAs were significantly altered during the process of H/R… read more here.
Keywords: excessive autophagy; mir 30b; propofol upregulates; microrna 30b ... See more keywords