A novel mechanism of sildenafil improving the excessive proliferation and H2S production in pulmonary arterial smooth muscle cells.
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DOI: 10.1097/fjc.0000000000000714
Abstract: The dysregulation of pulmonary arterial vasoactive mediators or excessive proliferation of pulmonary arterial smooth muscle cells (PASMCs) might result in contraction or remodeling of pulmonary blood vessels, leading to related lung diseases. Recent studies suggest… read more here.
Keywords: cbs; pulmonary arterial; excessive proliferation; sildenafil ... See more keywords