Excessive self-grooming, gene dysregulation and imbalance between the striosome and matrix compartments in the striatum of Shank3 mutant mice
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DOI: 10.3389/fnmol.2023.1139118
Abstract: Autism is characterised by atypical social communication and stereotyped behaviours. Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are detected in 1-2% of patients with autism and intellectual disability (ID), but the mechanisms… read more here.
Keywords: imbalance; excessive self; mice; self grooming ... See more keywords