The guanine nucleotide exchange factor Vav3 modulates oligodendrocyte precursor differentiation and supports remyelination in white matter lesions
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DOI: 10.1002/glia.23548
Abstract: The tightly controlled processes of myelination and remyelination require the participation of the cytoskeleton. The reorganization of the cytoskeleton is controlled by small GTPases of the RhoA family. Here, we report that Vav3, a Rho… read more here.
Keywords: guanine nucleotide; nucleotide exchange; remyelination; exchange factor ... See more keywords
WBSCR16 Is a Guanine Nucleotide Exchange Factor Important for Mitochondrial Fusion.
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DOI: 10.1016/j.celrep.2017.06.090
Abstract: Regulated inter-mitochondrial fusion/fission is essential for maintaining optimal mitochondrial respiration and control of apoptosis and autophagy. In mammals, mitochondrial fusion is controlled by outer membrane GTPases MFN1 and MFN2 and by inner membrane (IM) GTPase… read more here.
Keywords: important mitochondrial; nucleotide exchange; guanine nucleotide; exchange factor ... See more keywords
Integration of Fungus-Specific CandA-C1 into a Trimeric CandA Complex Allowed Splitting of the Gene for the Conserved Receptor Exchange Factor of CullinA E3 Ubiquitin Ligases in Aspergilli
Sign Up to like & getrecommendations! Published in 2019 at "mBio"
DOI: 10.1128/mbio.01094-19
Abstract: Aspergillus species are important for biotechnological applications, like the production of citric acid or antibacterial agents. Aspergilli can cause food contamination or invasive aspergillosis to immunocompromised humans or animals. Specific treatment is difficult due to… read more here.
Keywords: exchange; canda; canda complex; exchange factor ... See more keywords