The TRAPP complexes: oligomeric exchange factors that activate the small GTPases Rab1 and Rab11
Sign Up to like & getrecommendations! Published in 2022 at "Febs Letters"
DOI: 10.1002/1873-3468.14553
Abstract: The Transport Protein Particle (TRAPP) complexes are highly conserved multisubunit complexes that act as nucleotide exchange factors (GEFs) for Rab GTPases. They act in both protein secretion and autophagy and have also been proposed to… read more here.
Keywords: trapp complexes; complexes oligomeric; oligomeric exchange; exchange factors ... See more keywords
Nucleotide Exchange Factors for Hsp70 Chaperones.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7477-1_13
Abstract: The ATPase cycle of Hsp70 chaperones controls their transient association with substrates and thus governs their function in protein folding. Nucleotide exchange factors (NEFs) accelerate ADP release from Hsp70, which results in rebinding of ATP… read more here.
Keywords: nucleotide exchange; atpase; hsp70 chaperones; exchange factors ... See more keywords
Family-wide Analysis of the Inhibition of Arf Guanine Nucleotide Exchange Factors with Small Molecules: Evidence of Unique Inhibitory Profiles.
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DOI: 10.1021/acs.biochem.7b00706
Abstract: Arf GTPases and their guanine nucleotide exchange factors (ArfGEFs) are major regulators of membrane traffic and organelle structure in cells. They are associated with a variety of diseases and are thus attractive therapeutic targets for… read more here.
Keywords: guanine nucleotide; nucleotide exchange; family wide; exchange factors ... See more keywords
Arabidopsis Flippases Cooperate with ARF GTPase Exchange Factors to Regulate the Trafficking and Polarity of PIN Auxin Transporters[OPEN]
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DOI: 10.1105/tpc.19.00869
Abstract: ALA3 and related flippases are important interactors and regulators of ADP ribosylation factor GTPase Exchange Factors regulating the polarity and trafficking of PIN auxin transporters and auxin-mediated development. Cell polarity is a fundamental feature of… read more here.
Keywords: exchange factors; polarity; pin; auxin ... See more keywords