Solute exchange through gap junctions lessens the adverse effects of inactivating mutations in metabolite-handling genes
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DOI: 10.1101/2022.03.15.484462
Abstract: Experimental inactivation of certain genes involved in metabolism attenuates cancer cell growth in vitro. However, loss-of-function mutations in metabolic pathways are not negatively selected in human cancers, indicating that these genes are not essential in… read more here.
Keywords: handling genes; solute exchange; exchange gap; gap junctions ... See more keywords