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Published in 2022 at "Neuropediatrics"
DOI: 10.1055/s-0041-1742156
Abstract: OBJECTIVE Severe neonatal hyperbilirubinemia can cause neurological disability or mortality if not effectively managed. Exchange transfusion (ET) is an efficient treatment to prevent bilirubin neurotoxicity. The purpose of this study was to evaluate outcomes in… read more here.
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Published in 2018 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000000875
Abstract: Background: Neonatal hyperbilirubinemia is a frequently encountered problem. Erythrocytes, especially reticulocytes are rich in copper (Cu) and magnesium (Mg) so its serum levels increase after hemolysis. Zinc (Zn) plays an important role in synthesis of… read more here.
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Published in 2018 at "Transfusion"
DOI: 10.1111/trf.14512
Abstract: Hyperleukocytosis is a serious, life‐threatening complication of pediatric acute leukemia that can cause neurologic injury, pulmonary leukostasis, metabolic derangements, and coagulopathy. Acute leukemia has the highest risk of mortality and morbidity at presentation when associated… read more here.
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Published in 2021 at "Vox Sanguinis"
DOI: 10.1111/vox.13085
Abstract: It is proposed that severe leucocytosis mainly contributes to pulmonary hypertension by blocking pulmonary capillaries and restricting blood flow. Exchange transfusion (ET) in pertussis has been demonstrated as a safe and useful technique for depleting… read more here.
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Published in 2020 at "Blood"
DOI: 10.1182/blood-2020-135978
Abstract: Introduction: Sickle cell disease (SCD) poses a considerable health burden in lower middle income country (LMIC) like India. One ICMR survey reported about 20% of children with SCD died by the age of two years… read more here.
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Published in 2020 at "Blood"
DOI: 10.1182/blood-2020-136098
Abstract: Sickle cell disease (SCD) is a severe hemoglobinopathy due to the production of abnormal hemoglobin S (HbS). Although red blood cell (RBC) dysfunction is the major contributor to disease, several studies highlighted the important role… read more here.
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Published in 2021 at "Blood advances"
DOI: 10.1182/bloodadvances.2021004338
Abstract: Sickle cell trait (SCT) is typically an asymptomatic carrier state, but sickling complications can occur under extreme conditions. Priapism is known to be associated with sickle cell disease (SCD); The link with SCT is less… read more here.
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Published in 2022 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2022.926793
Abstract: Hyperammonemia is a serious complication of methylmalonic acidemia, with high mortality and permanent neurological sequelae in survivors. Primary hospitals are often the first admission hospitals for these children but are limited by their experience and… read more here.
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Published in 2023 at "African Health Sciences"
DOI: 10.4314/ahs.v23i1.70
Abstract: Background: Neonatal jaundice is one of the most common physiologic problems requiring medical attention in newborns. It is benign in most cases; however, high levels of bilirubin are neurotoxic and can lead to serious brain… read more here.