Amyloid Beta Alters Prefrontal-dependent Functions Along with its Excitability and Synaptic Plasticity in Male Rats
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DOI: 10.2139/ssrn.4006018
Abstract: Prefrontal cortex (PFC)-related functions, such as working memory (WM) and cognitive flexibility (CF), are among the first to be altered at early stages of Alzheimer's disease (AD). Likewise, transgenic AD models carrying different AD-related mutations,… read more here.
Keywords: amyloid beta; pfc; excitability; synaptic plasticity ... See more keywords
Removal of perineuronal nets leads to altered neuronal excitability and synaptic transmission in the visual cortex with distinct time courses
Sign Up to like & getrecommendations! Published in 2022 at "Neuroscience Letters"
DOI: 10.2139/ssrn.4078812
Abstract: Parvalbumin-expressing (PV) interneurons fast inhibit excitatory neurons in various brain areas. Perineuronal nets (PNNs), accumulating around PV neurons, have been shown to play critical roles in neuronal function and plasticity. The cellular mechanisms underlying their… read more here.
Keywords: synaptic transmission; neuronal excitability; transmission; excitability synaptic ... See more keywords