Reversible Photothermal Modulation of Electrical Activity of Excitable Cells using Polydopamine Nanoparticles.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced materials"
DOI: 10.1002/adma.202008809
Abstract: Advances in the design and synthesis of nanomaterials with desired biophysicochemical properties can be harnessed to develop non-invasive neuromodulation technologies. Here, the reversible modulation of the electrical activity of neurons and cardiomyocytes is demonstrated using… read more here.
Keywords: excitable cells; electrical activity; modulation electrical; using polydopamine ... See more keywords
Passive Recording of Bioelectrical Signals from Non-Excitable Cells by Fluorescent Mirroring
Sign Up to like & getrecommendations! Published in 2023 at "Nano Letters"
DOI: 10.1021/acs.nanolett.2c05053
Abstract: Bioelectrical variations trigger different cell responses, including migration, mitosis, and mutation. At the tissue level, these actions result in phenomena such as wound healing, proliferation, and pathogenesis. Monitoring these mechanisms dynamically is highly desirable in… read more here.
Keywords: cell; signals non; non excitable; recording bioelectrical ... See more keywords
NanoMEA: a tool for high-throughput, electrophysiological phenotyping of patterned excitable cells.
Sign Up to like & getrecommendations! Published in 2019 at "Nano letters"
DOI: 10.1021/acs.nanolett.9b04152
Abstract: Matrix nanotopographical cues are known to regulate the structure and function of somatic cells derived from human pluripotent stem cell (hPSC) sources. High-throughput electrophysiological analysis of excitable cells derived from hPSCs is possible via multielectrode… read more here.
Keywords: excitable cells; throughput; throughput electrophysiological; tool ... See more keywords
Sequential compound fusion and kiss-and-run mediate exo- and endocytosis in excitable cells
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abm6049
Abstract: Vesicle fusion at preestablished plasma membrane release sites releases transmitters and hormones to mediate fundamental functions like neuronal network activities and fight-or-flight responses. This half-a-century-old concept—fusion at well-established release sites in excitable cells—needs to be… read more here.
Keywords: sequential compound; compound; fusion; excitable cells ... See more keywords
Exocytosis, Endocytosis, and Their Coupling in Excitable Cells
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2017.00109
Abstract: Evoked exocytosis in excitable cells is fast and spatially confined and must be followed by coupled endocytosis to enable sustained exocytosis while maintaining the balance of the vesicle pool and the plasma membrane. Various types… read more here.
Keywords: excitable cells; coupling excitable; exocytosis endocytosis; endocytosis ... See more keywords
Highly Parallelized, Multicolor Optogenetic Recordings of Cellular Activity for Therapeutic Discovery Applications in Ion Channels and Disease-Associated Excitable Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.896320
Abstract: Optogenetic assays provide a flexible, scalable and information rich approach to probe compound effects for ion channel drug targets in both heterologous expression systems and associated disease relevant cell types. Despite the potential utility and… read more here.
Keywords: therapeutic discovery; parallelized multicolor; swarm; excitable cells ... See more keywords