Geometry-Dependent Arrhythmias in Electrically Excitable Tissues.
Sign Up to like & getrecommendations! Published in 2018 at "Cell systems"
DOI: 10.1016/j.cels.2018.08.013
Abstract: Little is known about how individual cells sense the macroscopic geometry of their tissue environment. Here, we explore whether long-range electrical signaling can convey information on tissue geometry to individual cells. First, we studied an… read more here.
Keywords: arrhythmias electrically; excitable tissues; geometry dependent; dependent arrhythmias ... See more keywords
Generation and customization of biosynthetic excitable tissues for electrophysiological studies and cell-based therapies.
Sign Up to like & getrecommendations! Published in 2018 at "Nature protocols"
DOI: 10.1038/nprot.2018.016
Abstract: We describe a two-stage protocol to generate electrically excitable and actively conducting cell networks with stable and customizable electrophysiological phenotypes. Using this method, we have engineered monoclonally derived excitable tissues as a robust and reproducible… read more here.
Keywords: excitable tissues; ion channels; stage protocol; protocol ... See more keywords