Current and Future Landscape of SERCAs' Functions in Non‐Excitatory Cells and Diseases
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DOI: 10.1002/bies.70029
Abstract: Calcium (Ca2+) signaling as the primary intracellular second messenger orchestrates a myriad of physiological processes. Maintaining Ca2+ homeostasis relies on Ca2+ channels, pumps, exchangers, and buffers. Sarco/endoplasmic reticulum Ca2+‐ATPases (SERCAs or ATP2A) encoded by ATP2A1,… read more here.
Keywords: excitatory cells; non excitatory; ca2 signaling; current future ... See more keywords
Bursting of excitatory cells is linked to interictal epileptic discharge generation in humans
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-022-10319-4
Abstract: Knowledge about the activity of single neurons is essential in understanding the mechanisms of synchrony generation, and particularly interesting if related to pathological conditions. The generation of interictal spikes—the hypersynchronous events between seizures—is linked to… read more here.
Keywords: cells linked; generation; bursting excitatory; discharge ... See more keywords