Synaptic adhesion molecules and excitatory synaptic transmission
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Neurobiology"
DOI: 10.1016/j.conb.2017.03.005
Abstract: Synaptic adhesion molecules have been extensively studied for their contribution to the regulation of synapse development through trans-synaptic adhesions. However, accumulating evidence increasingly indicates that synaptic adhesion molecules are also involved in the regulation of… read more here.
Keywords: synaptic transmission; adhesion molecules; synaptic adhesion; excitatory synaptic ... See more keywords
Activated leukocyte cell adhesion molecule is involved in excitatory synaptic transmission and plasticity in the rat spinal dorsal horn
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2017.07.015
Abstract: Activated leukocyte cell adhesion molecule (ALCAM), a member of type I transmembrane immunoglobulin superfamily of cell adhesion molecule, is expressed in the surface membrane of various cell types including neurons. In the spinal cord dorsal… read more here.
Keywords: transmission; synaptic transmission; cell adhesion; adhesion molecule ... See more keywords
Orexin receptors mediate long-term depression of excitatory synaptic transmission in the spinal cord dorsal horn
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2017.08.068
Abstract: Neuropeptides orexin-A and -B are related to the regulation of sleep/wakefulness and feeding behaviors. Recently, the peptides have also been shown to yield antinociceptive effects in various pain models. However, it is not clear whether… read more here.
Keywords: term; long term; synaptic transmission; term depression ... See more keywords
Syringaresinol suppresses excitatory synaptic transmission and picrotoxin-induced epileptic activity in the hippocampus through presynaptic mechanisms
Sign Up to like & getrecommendations! Published in 2018 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2017.12.014
Abstract: ABSTRACT Many neuromodulating drugs acting on the nervous system originate from botanical sources. These plant‐derived substances modulate the activity of receptors, ion channels, or transporters in neurons. Their properties make the substances useful for medicine… read more here.
Keywords: synaptic transmission; syr; suppresses excitatory; activity ... See more keywords
Autism spectrum disorder-like behavior caused by reduced excitatory synaptic transmission in pyramidal neurons of mouse prefrontal cortex
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-18861-3
Abstract: Autism spectrum disorder (ASD) is thought to result from deviation from normal development of neural circuits and synaptic function. Many genes with mutation in ASD patients have been identified. Here we report that two molecules… read more here.
Keywords: transmission; reduced excitatory; pyramidal neurons; synaptic transmission ... See more keywords
Very low concentrations of ethanol suppress excitatory synaptic transmission in rat visual cortex
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Neuroscience"
DOI: 10.1111/ejn.13557
Abstract: Ethanol is one of the most commonly used substances in the world. Behavioral effects of alcohol are well described, however, cellular mechanisms of its action are poorly understood. There is an apparent contradiction between measurable… read more here.
Keywords: transmission; transmission neocortex; synaptic transmission; concentrations ethanol ... See more keywords
Scn2a severe hypomorphic mutation decreases excitatory synaptic input and causes autism-associated behaviors
Sign Up to like & getrecommendations! Published in 2021 at "JCI Insight"
DOI: 10.1172/jci.insight.150698
Abstract: SCN2A, encoding the neuronal voltage-gated Na+ channel NaV1.2, is one of the most commonly affected loci linked to autism spectrum disorders (ASDs). Most ASD-associated mutations in SCN2A are loss-of-function mutations, but studies examining how such… read more here.
Keywords: voltage gated; scn2a; scn2a 1898; synaptic input ... See more keywords
Ovariectomy reduces cholinergic modulation of excitatory synaptic transmission in the rat entorhinal cortex
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0271131
Abstract: Estrogens are thought to contribute to cognitive function in part by promoting the function of basal forebrain cholinergic neurons that project to the hippocampus and cortical regions including the entorhinal cortex. Reductions in estrogens may… read more here.
Keywords: ovariectomy; entorhinal cortex; excitatory synaptic; cortex ... See more keywords
BDNF enhances electrophysiological activity and excitatory synaptic transmission of RA projection neurons in adult male zebra finches
Sign Up to like & getrecommendations! Published in 2022 at "Brain Research"
DOI: 10.2139/ssrn.4211156
Abstract: The singing of songbirds is a complex vocal behavior. It was reported that brain-derived neurotrophic factor (BDNF), a key neurotrophic factor involved in neuronal survival and activity, plays an important role in regulation of songbirds'… read more here.
Keywords: synaptic transmission; electrophysiological activity; excitatory synaptic; activity ... See more keywords
Selective inhibition of excitatory synaptic transmission alters the emergent bursting dynamics of in vitro neural networks
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neural Circuits"
DOI: 10.3389/fncir.2023.1020487
Abstract: Neurons in vitro connect to each other and form neural networks that display emergent electrophysiological activity. This activity begins as spontaneous uncorrelated firing in the early phase of development, and as functional excitatory and inhibitory… read more here.
Keywords: network; neural networks; inhibition; synaptic transmission ... See more keywords
Neuronal Nitric Oxide Synthase Knockdown Within Basolateral Amygdala Induces Autistic-Related Phenotypes and Decreases Excitatory Synaptic Transmission in Mice
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2020.00886
Abstract: Autism spectrum disorder (ASD) is a heterogeneous group of neurodevelopmental disorders characterized by deficits in communication, impaired social interaction, and repetitive or restricted interests and behaviors. We have recently shown that neuronal nitric oxide synthase… read more here.
Keywords: basolateral amygdala; synaptic transmission; mice; excitatory synaptic ... See more keywords