Priming the cardiodynamic phase of pulmonary oxygen uptake through voluntary modulations of the respiratory pump at the onset of exercise
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Physiology"
DOI: 10.1113/ep089180
Abstract: What is the central question of this study? The initial increase in oxygen uptake ( V̇O2 ) at exercise onset results from pulmonary perfusion changes secondary to an increased venous return. Breathing mechanics contribute to… read more here.
Keywords: exercise onset; oxygen uptake; onset; exercise ... See more keywords
Phosphodiesterase-5 inhibition preserves exercise-onset vasodilator kinetics when NOS activity is reduced.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.00483.2017
Abstract: Nitric oxide (NO)-mediated vasodilation contributes to the rapid rise in muscle blood flow at exercise onset. This occurs via increased cyclic guanosine monophosphate (cGMP), which is catabolized by phosphodiesterase-5 (PDE-5). Whether PDE-5 limits exercise vasodilation… read more here.
Keywords: onset kinetics; inhibition; vasodilation; exercise onset ... See more keywords