Esculentoside A exerts anti‐inflammatory activity in microglial cells
Sign Up to like & getrecommendations! Published in 2017 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2017.08.014
Abstract: Abstract Esculentoside A (EsA) is a saponin isolated from the roots of Phytolacca esculenta. This study was designed to evaluate the pharmacological effects of EsA on lipopolysaccharide (LPS)‐stimulated BV2 microglia and primary microglia cells. Our… read more here.
Keywords: anti inflammatory; primary microglia; bgr; esculentoside exerts ... See more keywords
Alternol, a natural compound, exerts an anti‐tumour effect on osteosarcoma by modulating of STAT3 and ROS/MAPK signalling pathways
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.12957
Abstract: Osteosarcoma (OS) is the most frequent primary malignant bone tumour. Alternol, a novel compound purified from microbial fermentation products exerts anti‐tumour effects across several cancer types. The effect of alternol on human OS remains to… read more here.
Keywords: tumour effect; signalling pathways; exerts anti; effect ... See more keywords
Berbamine Exerts an Anti-Oncogenic Effect on Pancreatic Cancer by Regulating Wnt and DNA Damage-Related Pathways.
Sign Up to like & getrecommendations! Published in 2022 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520622666220509174306
Abstract: OBJECTIVE This study aimed to determine the effects of berbamine on pancreatic cancer as well as the underlying mechanisms. METHODS The pancreatic cancer cells were treated with different concentrations of berbamine and then subjected to… read more here.
Keywords: exerts anti; effect; pancreatic cancer; berbamine exerts ... See more keywords
Deoxypodophyllotoxin Exerts Anti-Cancer Effects on Colorectal Cancer Cells Through Induction of Apoptosis and Suppression of Tumorigenesis
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20112612
Abstract: Deoxypodophyllotoxin (DPT) is a cyclolignan compound that exerts anti-cancer effects against various types of cancers. DPT induces apoptosis and inhibits the growth of breast, brain, prostate, gastric, lung, and cervical tumors. In this study, we… read more here.
Keywords: tumorigenesis; cancer effects; apoptosis; exerts anti ... See more keywords
Blocking of Caspases Exerts Anti-Inflammatory Effects on Periodontal Cells
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12071045
Abstract: Periodontitis is an inflammatory process that is associated with caspase activity. Caspases could thus become molecular targets for the modulation of the inflammatory response to harmful factors, such as lipopolysaccharides (LPS) and TNFα. Here, the… read more here.
Keywords: exerts anti; vad fmk; inflammatory response; caspases exerts ... See more keywords
MMPP Exerts Anti-Inflammatory Effects by Suppressing MD2-Dependent NF-κB and JNK/AP-1 Pathways in THP-1 Monocytes
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16040480
Abstract: (E)-2-methoxy-4-[3-(4-methoxyphenyl) prop-1-en-1-yl] phenol (MMPP), a novel synthetic analog of (E)-2,4-bis(p-hydroxyphenyl)-2-butenal (BHPB), exerts anti-inflammatory and anticancer effects by downregulating the STAT3 pathway. It has also been recently reported that MMPP can act as a PPAR agonist… read more here.
Keywords: exerts anti; mmpp; thp monocytes; jnk pathways ... See more keywords