Upregulation of miR-215 exerts neuroprotection effects against ischemic injury via negative regulation of Act1/IL-17RA signaling
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DOI: 10.1016/j.neulet.2017.10.046
Abstract: OBJECTIVE This study investigated the role of miR-215 and nuclear factor-κB activator (Act)1 and their mechanisms of action in ischemic stroke. METHODS Cell viability was examined with the 3-(4,5-dimethythiazol-. 2-yl)-2,5-diphenyl tetrazolium bromide assay; cell apoptosis… read more here.
Keywords: upregulation mir; ischemic injury; mir 215; 215 exerts ... See more keywords
Roflupram exerts neuroprotection via activation of CREB/PGC‐1α signalling in experimental models of Parkinson's disease
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DOI: 10.1111/bph.14983
Abstract: Roflupram improves cognition and limits neuroinflammation in the brain. However, the beneficial effects of roflupram on Parkinson's disease (PD) remain unknown. Therefore, we aimed to elucidate the pharmacological effects and mechanisms of action of ROF… read more here.
Keywords: exerts neuroprotection; roflupram exerts; experimental models; parkinson disease ... See more keywords