Cancer labs reach beyond exhausted T cells
Sign Up to like & getrecommendations! Published in 2020 at "Nature Methods"
DOI: 10.1038/s41592-020-0800-5
Abstract: T cells race to the scene in cancer and infection. To tease out what is special in cancer, scientists widen their scope and tool sets. read more here.
Keywords: exhausted cells; reach beyond; labs reach; beyond exhausted ... See more keywords
Dissecting the heterogeneity of exhausted T cells at the molecular level.
Sign Up to like & getrecommendations! Published in 2022 at "International immunology"
DOI: 10.1093/intimm/dxac016
Abstract: Our understanding of mechanisms underlying T cell exhaustion has been refined by analysis of exhausted T cells at the molecular level. The development and functions of exhausted T cells are regulated by a number of… read more here.
Keywords: cell; cells molecular; exhausted cells; dissecting heterogeneity ... See more keywords
Abstract 4436: A novel antibody-enabled dual precision targeted protein stabilization (TPS2) that augments anti-tumor immune response by targeting CBL-B inhibitor to exhausted T cells while blocking checkpoint molecule, PD-1
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-4436
Abstract: It is well-established that T cells play a key role in the success of cancer immunotherapies. The goals of T cell-targeting therapies have been to restore the effector function of tumor-specific T cells that are… read more here.
Keywords: cbl; exhausted cells; novel antibody; tumor ... See more keywords
Baseline Circulating Activated TFH and Tissue-Like Exhausted B Cells Negatively Correlate With Meningococcal C Conjugate Vaccine Induced Antibodies in HIV-Infected Individuals
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.02500
Abstract: Since 2006, meningococcal serogroup C (MenC) conjugate (MCC) vaccines have been supplied by the Brazilian government for HIV-infected children under 13 years old. For measuring protection against MenC, the serum bactericidal antibody (SBA) assay is… read more here.
Keywords: exhausted cells; tfh cells; vaccine induced; vaccine ... See more keywords