Articles with "exhaustion" as a keyword



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The mediating effect of exhaustion in the relationship between effort‐reward imbalance and turnover intentions: A 4‐year longitudinal study from Sweden

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Published in 2021 at "Journal of Occupational Health"

DOI: 10.1002/1348-9585.12203

Abstract: Abstract Objectives Earlier studies suggest that imbalance between effort and reward at work associates with exhaustion. Others have found that exhaustion increases turnover intentions; an important precursor of actual turnover that also associates with counterproductive… read more here.

Keywords: turnover intentions; effort reward; turnover; exhaustion ... See more keywords
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A Nanotherapeutic Strategy to Reverse NK Cell Exhaustion.

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Published in 2023 at "Advanced materials"

DOI: 10.1002/adma.202211370

Abstract: As a specialized immune effector cell, natural killer (NK) cells play a very important role in immunotherapy, but tumor immunosuppression caused by abnormal expression of cancer cells seriously weakens its therapeutic effect and leads to… read more here.

Keywords: cell; reverse cell; exhaustion; cell exhaustion ... See more keywords
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Inhibition of Calcium Signaling Prevents Exhaustion and Enhances Anti‐Leukemia Efficacy of CAR‐T Cells via SOCE‐Calcineurin‐NFAT and Glycolysis Pathways

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Published in 2022 at "Advanced Science"

DOI: 10.1002/advs.202103508

Abstract: Abstract Chimeric antigen receptor (CAR) T cells are potent agents for recognizing and eliminating tumors, and have achieved remarkable success in the treatment of patients with refractory leukemia and lymphoma. However, dysfunction of T cells,… read more here.

Keywords: soce calcineurin; calcium; exhaustion; car ... See more keywords
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Intraindividual associations between active social media use, exhaustion, and bedtime vary according to age-A longitudinal study across adolescence.

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Published in 2022 at "Journal of adolescence"

DOI: 10.1002/jad.12033

Abstract: INTRODUCTION The majority of adolescents engage with others online, and using social media is one of their top activities. However, there is little longitudinal evidence addressing whether active social media use is associated with study-related… read more here.

Keywords: social media; exhaustion; active social; adolescence ... See more keywords
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γδ T cell exhaustion: Opportunities for intervention

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Published in 2022 at "Journal of Leukocyte Biology"

DOI: 10.1002/jlb.5mr0722-777r

Abstract: T lymphocytes are the key protective contributors in chronic infection and tumor, but experience exhaustion by persistent antigen stimulation. As an unconventional lineage of T cells, γδ T cells can rapidly response to varied infectious… read more here.

Keywords: exhaustion opportunities; exhaustion; opportunities intervention; cell exhaustion ... See more keywords
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Effluent-free deep dyeing of cotton fabric with cacao husk extracts using the Taguchi optimization method

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Published in 2020 at "Cellulose"

DOI: 10.1007/s10570-020-03525-8

Abstract: Abstract Textile dyehouses are under scrutiny because they discharge colored and hazardous effluents to waterways. There is a need to develop an alternative dyeing system that does not produce any hazardous effluent. The waterless dyeing… read more here.

Keywords: husk extracts; cotton fabric; method; cacao husk ... See more keywords
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Accelerated Maturation, Exhaustion, and Senescence of T cells in 22q11.2 Deletion Syndrome.

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Published in 2021 at "Journal of clinical immunology"

DOI: 10.1007/s10875-021-01154-9

Abstract: PURPOSE 22q11.2 deletion syndrome (22q11.2DS) is a primary immunodeficiency characterized chiefly by the hypoplasia of the thymus resulting in T cell lymphopenia, increased susceptibility to infections, and higher risk of autoimmune diseases. The irregular thymic… read more here.

Keywords: deletion syndrome; cell; 22q11 2ds; senescence ... See more keywords
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Unraveling the Signaling Balance of Activation and Exhaustion of CAR T Cells.

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Published in 2020 at "Cancer cell"

DOI: 10.1016/j.ccell.2020.01.006

Abstract: CAR T cells with different costimulation domains have proven clinical efficacy in leukemia and lymphoma but have different kinetics of activation, antigen sensitivity, and susceptibility to exhaustion. Two recent studies identified that these functions are shaped… read more here.

Keywords: unraveling signaling; car; activation; car cells ... See more keywords
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Tumor-infiltrating CD8+ T cell antitumor efficacy and exhaustion: molecular insights.

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Published in 2021 at "Drug discovery today"

DOI: 10.1016/j.drudis.2021.01.002

Abstract: Host immunity has an essential role in the clinical management of cancers. Therefore, it is advantageous to choose therapies that can promote tumor cell death and concurrently boost host immunity. The dynamic tumor microenvironment (TME)… read more here.

Keywords: cd8 cell; tumor infiltrating; exhaustion; cell ... See more keywords
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How does emotional exhaustion influence work stress? Relationships between stressor appraisals, hedonic tone, and fatigue in nurses' daily tasks: A longitudinal cohort study.

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Published in 2017 at "International journal of nursing studies"

DOI: 10.1016/j.ijnurstu.2017.07.002

Abstract: BACKGROUND Work-related stress is a prevalent condition in the nursing profession, and its influence may vary according to changeable individual and situational factors. It is, therefore, important to investigate the real-time momentary changes in these… read more here.

Keywords: work; task performed; hedonic tone; exhaustion ... See more keywords
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T cell exhaustion implications during transplantation.

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Published in 2018 at "Immunology letters"

DOI: 10.1016/j.imlet.2018.08.003

Abstract: Exhaustion of lymphocyte function, particularly T cell exhaustion, due to prolonged exposure to a high load of foreign antigen is commonly seen during chronic viral infection as well as antitumor immune responses. This phenomenon has… read more here.

Keywords: exhaustion implications; exhaustion; implications transplantation; cell exhaustion ... See more keywords