Cochlear connexin 30 homomeric and heteromeric channels exhibit distinct assembly mechanisms
Sign Up to like & getrecommendations! Published in 2019 at "Mechanisms of Development"
DOI: 10.1016/j.mod.2018.10.001
Abstract: Many of the mutations in GJB2 and GJB6, which encode connexins 26 and 30 (Cx26 and Cx30), impair the formation of membrane channels and cause autosomal syndromic and non-syndromic hearing loss. In cochlear non-sensory supporting… read more here.
Keywords: homomeric heteromeric; distinct assembly; exhibit distinct; heteromeric gap ... See more keywords
PD‐1‐induced proliferating T cells exhibit a distinct transcriptional signature
Sign Up to like & getrecommendations! Published in 2021 at "Immunology"
DOI: 10.1111/imm.13388
Abstract: Ligation of the inhibitory receptor PD‐1 on T cells results in the inhibition of numerous cellular functions. Despite the overtly inhibitory outcome of PD‐1 signalling, there are additionally a collection of functions that are activated.… read more here.
Keywords: distinct transcriptional; induced proliferating; exhibit distinct; proliferating cells ... See more keywords