Extracellular Matrix Stiffness Exists in a Feedback Loop that Drives Tumor Progression.
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DOI: 10.1007/978-3-319-95294-9_4
Abstract: Cells communicate constantly with their surrounding extracellular matrix (ECM) to maintain homeostasis, using both mechanical and chemical signals. In cancer, abnormal signaling leads to stiffening of the ECM. A stiff microenvironment affects many aspects of… read more here.
Keywords: matrix stiffness; feedback loop; extracellular matrix; matrix ... See more keywords