TCF/LEF regulation of the topologically associated domain ADI promotes mESCs to exit the pluripotent ground state.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109705
Abstract: Mouse embryonic stem cells (mESCs) can be maintained in vitro in defined N2B27 medium supplemented with two chemical inhibitors for GSK3 and MEK (2i) and the cytokine leukemia inhibitory factor (LIF), which act synergistically to promote… read more here.
Keywords: tcf lef; topologically associated; associated domain; exit pluripotent ... See more keywords